Sure, i think we mean the same thing by downsampling... I was not referring to lowering bit depth resolution but rather changing the sample rate of an already sampled signal. So drop the SR from 44.1kHz to 11025Hz or for example. In old samplers the codec often didnt support high SRs like ADCs do today. So yeah, if you can deal with aliasing in a patch, then your good.
Let me know if I completely misunderstood you...